Zalcitabine
PubChem CID | 24066 |
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Structure |
Find Similar Structures
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Chemical Safety |
Laboratory Chemical Safety Summary (LCSS) Datasheet
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Molecular Formula | C9H13N3O3 |
Synonyms |
zalcitabine 7481-89-2 Dideoxycytidine 2′,3′-DIDEOXYCYTIDINE ddCyd |
Molecular Weight | 211.22 |
Zalcitabine is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zalcitabine preferentially inhibits the gamma form of DNA polymerase present in tumor cell mitochondria, resulting in the inhibition of tumor cell mitochondrial DNA replication and tumor cell death. (NCI04)