Zalcitabine

Zalcitabine

PubChem CID 24066
Structure
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Chemical Safety
Laboratory Chemical Safety Summary (LCSS) Datasheet
Molecular Formula C9H13N3O3
Synonyms

zalcitabine

7481-89-2

Dideoxycytidine

2′,3′-DIDEOXYCYTIDINE

ddCyd

Molecular Weight 211.22

Zalcitabine is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zalcitabine preferentially inhibits the gamma form of DNA polymerase present in tumor cell mitochondria, resulting in the inhibition of tumor cell mitochondrial DNA replication and tumor cell death. (NCI04)

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