Valdecoxib
| PubChem CID | 119607 |
|---|---|
| Structure |
Find Similar Structures
|
| Chemical Safety |
Laboratory Chemical Safety Summary (LCSS) Datasheet |
| Molecular Formula | C16H14N2O3S |
| Synonyms |
Valdecoxib 181695-72-7 Bextra 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide SC 65872 |
| Molecular Weight | 314.4 |
Valdecoxib is a sulfonamide derivative and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. Valdecoxib selectively binds to and inhibits cyclooxygenase (COX)-2, thereby preventing the conversion of arachidonic acid into prostaglandins, which are involved in the regulation of pain, inflammation, and fever. This NSAID does not inhibit COX-1 at therapeutic concentrations and therefore does not interfere with blood coagulation.