TETRASODIUM EDTA
TETRASODIUM EDTA
EC / List no.: 200-573-9
CAS no.: 64-02-8
Tetrasodium EDTA, also in powder form, is one of the most versatile, and widely used, chelating agents.
Tetrasodium EDTA often utilized in personal care products to control metal ions across a very broad pH range.
Tetrasodium EDTA functions by bonding to metal ions, and inactivating them, to prevent deterioration of the product, which also prevents the metal ions from depositing onto the skin and hair.
In personal care products, these agents improve: effectiveness, stability, hard water performance, rinseability, clarity, fragrance integrity, and shelf life of formulations.
Tetrasodium EDTA can also be used to neutralize Carbomer, or raise the pH of personal care formulations.
Please see the PDF for information on Tetrasodium EDTA chelant capability in order to determine the quantity required for your application.
Selecting the quantity is too product dependent for us to list a usage amount, though typical usage is 0.2 to 0.5%, with 0.2% being effective in most applications, in personal care products.
The dry crystalline version of Tetrasodium EDTA is useful in formulation of dry products or in applications where the total water content of the final product must be kept to a minimum.
Tetrasodium EDTA performs over a wide variety of pH systems and is the product of choice for applications where product purity is especially important.
ATAMAN CHEMICALS is your local expert and supplier of Tetrasodium EDTA.
CAS Number
64-02-8 (anhydrous)
13235-36-4 (tetrahydrate)
Synonym: EDTA tetrasodium salt, Edathamil, Tetrasodium EDTA, Tetrasodium ethylenediaminetetraacetate hydrate
Tetrasodium EDTA is the salt resulting from the neutralization of ethylenediaminetetraacetic acid with four equivalents of sodium hydroxide (or an equivalent sodium base).
It is a white solid that is highly soluble in water. Commercial samples are often hydrated, e.g. Na4EDTA.4H2O.
The properties of solutions produced from the anhydrous and hydrated forms are the same, provided they are at the same pH.
It is used as a source of the chelating agent EDTA4-.
A 1% aqueous solution has a pH of approximately 11.3. When dissolved in neutral water, it converts partially to H2EDTA2-.
Ethylenediaminetetraacetic acid is produced commercially via the intermediacy of tetrasodium EDTA
DTA, Ethylenediaminetetraacetic acid is a molecule which complexes metal ions in aqueous environments.
It is available in four neutralizations, two of which, Disodium EDTA and Tetrasodium EDTA, are commonly used in the cosmetics.
Generally, the choice of which product to use is determined by the pH of your product. Tetrasodium EDTA is recommended for alkaline products, like most handcrafted soap.
It can also be used in creams, lotions and surfactant systems.
If your formulation is clear or transparent, it may be preferred over Disodium ETDA as it is much more soluble in water.
Either form works synergistically with your preservative to improve preservative efficacy.
In soaps, it can counteract the defoaming action of hardness ions, reducing soap scum and improving lather.
INCI: Tetrasodium EDTA
Name: Tetrasodium EDTA
CAS Number: 64-02-8
Synonyms: Edetate sodium, Sodium edetate, Tetrasodium EDTA, Tetrasodium edetate, Tetrasodium ethylene diamine tetraacetate, (Ethylenedinitrilo)tetraacetic acid tetrasodium salt, Edathanil tetrasodium, Edetic acid tetrasodium salt, Ethylene diamine tetraacetic acid sodium salt, Ethylenebis(iminodiacetic acid) tetrasodium salt, Ethylenediaminetetraacetic acid, tetrasodium salt, Na4EDTA
Tetrasodium ETDA (which stands for ethylenediaminetetraacetic acid) is a water-soluble ingredient used as a “chelator,” which means it binds to certain mineral ions to inactivate them.
Through this action, it can prevent the deterioration of cosmetic and personal care products, as it stops the growth of mold and other microorganisms.
Tetrasodium EDTA also helps maintain clarity, protect fragrance compounds, and prevent rancidity. One of its main uses it to help personal care products work better in hard water.
TETRASODIUM EDTA
TETRASODIUM EDTA is classified as :
Chelating
CAS Number 64-02-8
EINECS/ELINCS No: 200-573-9
COSING REF No: 38569
INN Name: edetate sodium
Chem/IUPAC Name: Tetrasodium ethylenediaminetetraacetate
Tetrasodium EDTA is a commonly used chelating agent.
Tetrasodium EDTA is recommended for complex calcium and magnesium ions above pH 7, and for most common metal ions throughout the pH range.
Tetrasodium EDTA can also be used for complex iron to pH 8.5.
EDTA Tetrasodium Salt Liquid
Ethylenediamine tetraacetic acid, tetrasodium salt, tetrahydrate
Glycine, N,N’-1,2-ethanediylbis[N-(carboxymethyl)-, tetrasodium salt, tetrahydrate
Tetrasodium ethylenediamine tetraacetate
Laboratory technicians use the three ingredients mentioned above to synthesize EDTA, and then tetrasodium EDTA is derived from that.
You’ll find it in moisturizers, skin care and cleansing products, personal cleanliness products, bath soaps, shampoos and conditioners, hair dyes, hair bleaches, and many other products.
It’s also cleared for use in packaged foods, vitamins, and baby food.
Acetic acid, (ethylenedinitrilo)tetra-, tetrasodium salt
tetrasodium ethylene diamine tetraacetate
Tetrasodium ethylenediaminetetraacetate
tetrasodium ethylenediaminetetraacetate
ethylendiamintetraacetát tetrasodný (cs)
etilendiaminotetraacetat de tetrasodiu (ro)
etilendiaminotetraacetato de tetrasodio (es)
etilendiamminotetraacetato di tetrasodio (it)
etilenodiaminotetraacetato de tetrassódio (pt)
etylendiamintetraättiksyra, tetranatriumsalt (sv)
Tetranaatriumetüleendiamiintetraatsetaat (et)
tetranatrijev etilendiaminotetraacetat (sl)
tetranatrio etilendiamintetraetanoatas (lt)
tetranatrium-ethylendiamintetraacetat (da)
tetranatriumethyleendiaminetetraacetaat (nl)
Tetranatriumethylendiamintetraacetat (de)
Tetranatriumetyleenidiamiinitetra-asetaatti (fi)
tetranatriumetylendiamintetraacetat (no)
tetranátrium-etilén-diamin-tetraacetát (hu)
tetranátrium-etyléndiamíntetraacetát (sk)
tetranātrija etilēndiamīntetraacetāts (lv)
tetrasodium ethylene diamine tetraacetate (mt)
wersenian czterosodowy (pl)
éthylènediaminetétraacétate de tétrasodium (fr)
αιθυλενοδιαμινοετραοξικό νάτριο (el)
тетранатриев етилен диамин тетраацетат (bg)
CAS names
Glycine, N,N’-1,2-ethanediylbis[N-(carboxymethyl)-, sodium salt (1:4)
IUPAC names
Acido Etilendiaminotetraacético Sal Tetrasódica 4-hidrato
Edetate sodium; Versene; Aquamollin …
EDTA 4Na
EDTA Na4
EDTA tetrasodium salt
EDTA tetrasodium salt , (Ethylenedinitrilo)tetraacetic acid tetrasodium salt Acetic acid, (ethylenedinitrilo)tetra-, tetrasodium salt
EDTA-Na4
EDTA-Tetrasodium salt
EDTA4Na
ethylendiamintetraacetát tetrasodný
Ethylendiamintetraessigsäure, Tetranatriumsalz
ethylenediamine tetraacetic acid, tetrasodium salt
Ethylenediaminetetraacetic acid tetrasodium salt
Ethylenediaminetetraacetic acid tetrasodium salt dihydrate
Glycine, N,N’-1,2-ethanediylbis((N-(carboxymethyl)-, tetrasodium-salt
Glycine, N,N’-1,2-ethanediylbis[N-(carboxymethyl)-, tetrasodium salt
Sodium edetate
Sodium ethylenediaminetetraacetate, dihydrate
Tetra Sodium Ethylene Diamine Tetraacetate
Tetranatriumethylendiamintetra-acetat
tetrasodium 2,2′,2”,2”’- (ethane-1,2,diyldinitrilo) tetraacetate
tetrasodium 2,2′,2”,2”’-(ethane-1,2-diyldinitrilo)tetraacetate
tetrasodium 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetate
tetrasodium 2-[2-[bis(2-oxido-2-oxoethyl)amino]ethyl- (2-oxido-2-oxoethyl)amino]acetate
tetrasodium 2-[2-[bis(2-oxido-2-oxoethyl)amino]ethyl-(2-oxido-2-oxoethyl)amino] acetate
tetrasodium 2-[2-[bis(2-oxido-2-oxoethyl)amino]ethyl-(2-oxido-2-oxoethyl)amino]acetate
tetrasodium 2-[2-[bis(carboxylatomethyl)amino]ethyl-
tetrasodium 2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate
tetrasodium 2-[2-bis(2-oxido-2-oxoethyl)amino]ethyl-(2-oxido-2-oxoethyl)amino]acetate
tetrasodium 2[2-[bis(2-oxido-2-oxoethyl)amino]ethyl-(2-oxido-2-oxoethyl)amino]acetate
Tetrasodium EDTA
tetrasodium ethyelenediamine acetate
Tetrasodium ethylene diamine tetraacetate
tetrasodium ethylene diamine tetraacetate
TETRASODIUM ETHYLENEDIAMINETETRAACETATE
Tetrasodium ethylenediaminetetraacetate
tetrasodium ethylenediaminetetraacetate
tetrasodium ethylenediaminetetraacetate
Tetrasodium Ethylenediaminetetraacetate Dihydrate
Tetrasodium ethylenediaminetetraacetate hydrate
tetrasodium etylene diamine tetraacetate
tetrasodium {[2-(bis-carboxymethyl-amino)-ethyl]- carboxymethylamino}-acetate
tetrasodium2-[2-[bis(2-oxido-2-oxoethyl)amino]ethyl-(2-oxido-2-oxoethyl)amino]acetate
tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate
Tetrasodium{[2-(bis-carboxymethyl-amino)-ethyl]-carboxymethylamino}-acetate
tetresodium ethylene diamine tetraacetate
Trade names
Dabeersen Na4 30%L
Dabeersen Na4 40% L
Dabeersen Na4C2
Dabeersen Na4TD
Dissolvine 100-S
Dissolvine 100-s
Dissolvine 220-S
Dissolvine 240-S
Dissolvine E-39
Dissolvine E-39-K
Dissolvine NA
Dissolvine NA-X
EDTA 4Na 2H2O
EDTA-Tetrasodium salt (EDTA-4NA)
MASQUOL EDTA Na
MASQUOL EL 40
Tetrasodium ethylenediaminetetraacetate
Trilon B Powder
VERSENE 100 Chelanting Agent
VERSENE 100 XL Chelating Agent
VERSENE 100E Chelating Agent
VERSENE 100E LC Chelating Agent
VERSENE 220 Crystals Chelating Agent
VERSENE POWDER Chelating Agent
2,2′,2”,2”’-(1,2-Éthanediyldinitrilo)tetraacétate de tétrasodium [French] [ACD/IUPAC Name]
64-02-8 [RN]
Complexone [Trade name]
Edetate Sodium [USAN]
EDETIC ACID TETRASODIUM SALT
EDTA sodium
EDTA Tetrasodium
EDTA tetrasodium salt
Endrate tetrasodium
Ethylenediaminetetraacetic acid tetrasodium salt
Glycine, N,N’-1,2-ethanediylbis[N-(carboxymethyl)-, tetrasodium salt
N,N’-Ethylenediaminediacetic acid tetrasodium salt
Nervanaid B [Trade name]
Nullapon [Trade name]
TETRACEMATE TETRASODIUM
Tetranatrium ethylendiamintetraacetat [Czech]
Tetranatrium-2,2′,2”,2”’-(1,2-ethandiyldinitrilo)tetraacetat [German] [ACD/IUPAC Name]
Tetrasodium 2,2′,2”,2”’-(1,2-ethanediyldinitrilo)tetraacetate [ACD/IUPAC Name]
Tetrasodium 2,2′,2”,2”’-(ethane-1,2-diyldinitrilo)tetraacetate
Tetrasodium edetate
TETRASODIUM EDTA
Tetrasodium ethylenediaminetetraacetate
Tetrasodium salt EDTA
Tetrasodium salt of EDTA
(Ethylenedinitrilo)tetraacetic acid tetrasodium salt
[64-02-8]
200-573-9 [EINECS]
241-543-5 [EINECS]
Acetic acid, (ethylenedinitrilo)tetra-, tetrasodium salt
Aquamoline BC
Aquamollin
Calsol
Celon E
Celon H
Celon IS
Cheelox BF
Chelest 400
Chelon 100
Chemcolox 200
Clewat S 2
Clewat T
Conigon BC
D03946
Distol
Distol 8
Edathanil tetrasodium
Edetate sodium (USAN)
EDTA tetrasodium salt dihydrate
EDTA, SODIUM SALT
EDTA, tetrasodium
EDTA-Na4
EINECS 200-573-9
Ergon [Wiki]
Ergon B
Ethylene diamine tetra acetic acid tetra sodium salt
Ethylene diamine tetraacetic acid sodium salt
Ethylenebis(iminodiacetic acid) tetrasodium salt
Ethylenediaminetetraacetic acid, tetrasodium salt
ethylenediaminetetraaceticacidtetrasodiumsalt
Glycine, N,N’-1,2-ethanediylbis(N-(carboxymethyl)-, tetrasodium salt
Hamp-ene 100
Hamp-ene 100S
Hamp-ene 215
Hamp-ene 220
Hamp-ene Na4
Irgalon
Jsp000384
Kalex
Kemplex 100
Komplexon
Kutrilon CS
Metaquest C
MFCD00012460 [MDL number]
MFCD00150026 [MDL number]
MFCD00150027
N,N’-1,2-Ethanediylbis(N-(carboxymethyl)glycine) tetrasodium salt
N,N’-1,2-Ethanediylbis(N-(carboxymethyl)glycine), tetrasodium salt
N,N’-1,2-Ethanediylbis[N-(carboxymethyl)glycine] Tetrasodium Salt
Na4EDTA
Natrii edetas
Natrium aedeticum
Nervanaid B liquid
Nervanaid-B liquid
Nullapon B
Perma kleer 100
Perma-kleer 100
Perma-kleer tetra c
Perma-kleer tetra cp
pQuestex
Questex
Questex 4
SEQUESTRENE
Sequestrene 30A
Sequestrene Na 4
Sequestrene ST
Sodium (edetate de)
SODIUM 2,2′,2”,2”’-(ETHANE-1,2-DIYLBIS(AZANETRIYL))TETRAACETATE
Sodium edetate
Sodium EDTA
Sodium ethylenediaminetetraacetate
Sodium ethylenediaminetetraacetic acid
Sodium salt of ethylenediaminetetraacetic acid
Sodium2,2′,2”,2”’-(ethane-1,2-diylbis(azanetriyl))tetraacetate
Syntes 12A
Syntron B
Tetracemin
Tetranatrium ethylendiamintetraacetat [Czech]
Tetrasodium (ethylenedinitrilo)tetraacetate
tetrasodium 2-[2-[bis(2-keto-2-oxido-ethyl)amino]ethyl-(2-keto-2-oxido-ethyl)amino]acetate
tetrasodium 2-[2-[bis(2-oxido-2-oxoethyl)amino]ethyl-(2-oxido-2-oxoethyl)amino]acetate
tetrasodium 2-[2-[bis(2-oxido-2-oxo-ethyl)amino]ethyl-(2-oxido-2-oxo-ethyl)amino]acetate
tetrasodium 2-[2-[bis(2-oxido-2-oxo-ethyl)amino]ethyl-(2-oxido-2-oxo-ethyl)amino]ethanoate
Tetrasodium ethylene diamine tetraacetate
Tetrasodium Ethylenebis(iminodiacetate)
tetrasodium ethylenediamine(tetraacetate)
Tetrasodium ethylenediamine-N,N,N’,N’-tetraacetate
tetra-sodium ethylenediaminetetraacetate
Tetrasodium ethylenediaminetetracetate
TETRASODIUM ION(4-) EDTA
Tetrasodium salt of ethylenediaminetetracetic acid
Tetrine
Trilon B
TST
Tyclarosol
UNII:MP1J8420LU
UNII-MP1J8420LU
Versene
Warkeelate PS-42
Warkeelate PS-43
Warkeelate PS-47
Warkeelate S-42
Edetate sodium
Sodium edetate
64-02-8
EDTA tetrasodium
Ethylenediaminetetraacetic acid tetrasodium salt
Sequestrene
EDTA sodium
Sodium EDTA
Tetrasodium edetate
Versene 100
Versene 220
Na4EDTA
EDTA tetrasodium salt
TETRASODIUM EDTA
Tetrasodium ethylenediaminetetraacetate
Tetrasodium salt of EDTA
Trilon B
Monosodium edetate
Edetate Sodium [USAN]
UNII-MP1J8420LU
SODIUM ETHYLENEDIAMINETETRAACETATE
MP1J8420LU
EDTA, tetrasodium
67401-50-7
Aquamollin
Complexone
Irgalon
Komplexon
Nullapon
Questex
Tetracemin
Tetrine
Tyclarosol
Calsol
Distol
Edetate sodium (USAN)
Ergon
Kalex
Natrii edetas
Versene beads
Versene flake
Versene powder
Sequestrene ST
Aquamoline BC
Metaquest C
Nervanaid B
Glycine, N,N’-1,2-ethanediylbis(N-(carboxymethyl)-, sodium salt (1:4)
Nullapon B
Kutrilon CS
Natrium aedeticum
Syntron B
Cheelox BF
Clewat T
Conigon BC
Nullapon BFC
Sequestrene 30A
Celon E
Celon H
Ergon B
Questex 4
Celon IS
Endrate tetrasodium
Sequestrene Na 4
Distol 8
Nervanaid B liquid
Nervanaid-B liquid
Hamp-ene Na4
Warkeelate S-42
Nullapon BFC Xonc
Chemcolox 200
Versene 67
Versene FE 3
Perma kleer 100
Perma-kleer 100
Nullapon BF-12
Nullapon BF-78
Warkeelate PS-42
Warkeelate PS-43
Warkeelate PS-47
Clewat S 2
Edathanil tetrasodium
Syntes 12A
Buffer Concentrate, pH 7.00
Nullapon BFC Liquid
Cheelox BF-12
Cheelox BF-13
Cheelox BF-78
Cheelox BR-33
Chelest 400
Kemplex 100
Perma-kleer tetra cp
Sodium (edetate de)
Perma kleer tetra CP
Chelon 100
Hamp-ene 100S
Caswell No. 846
Hamp-ene 100
Hamp-ene 215
Hamp-ene 220
Tetracemate tetrasodium
Tetrasodium salt EDTA
Chemcolox 240 powder
edta tetrasodium salt hydrate
Nullapon BFC Xonc Beads
Perma kleer 50 crystals
ETHYLENEDIAMINETETRAACETICACIDTETRASODIUMSALT
Versene powder tetra sodium
Edetic acid tetrasodium salt
CCRIS 6797
HSDB 5003
EINECS 200-573-9
Tetrasodium ethylenediaminetetracetate
Sodium ethylenediaminetetraacetic acid
EPA Pesticide Chemical Code 039107
Tetrasodium (ethylenedinitrilo)tetraacetate
AI3-17182
Ethylene diamine tetraacetic acid sodium salt
Tetranatrium ethylendiamintetraacetat [Czech]
Glycine, N,N’-1,2-ethanediylbis[N-(carboxymethyl)-, sodium salt (1:4)
Sodium salt of ethylenediaminetetraacetic acid
Ethylenebis(iminodiacetic acid) tetrasodium salt
Ethylenediaminetetraacetic acid, tetrasodium salt
Tetrasodium salt of EDTA solution
Tetrasodium salt of ethylenediaminetetracetic acid
N,N’-Ethylenediaminediacetic acid tetrasodium salt
Tetranatrium ethylendiamintetraacetat
(Ethylenedinitrilo)tetraacetic acid tetrasodium salt
Tetrasodium ethylenediamine-N,N,N’,N’-tetraacetate
Tetrasodium(ethylenedinitrilo)tetraacetate
EDTA 4Na
N,N’-1,2-Ethanediylbis(N-(carboxymethyl)glycine) tetrasodium salt
Tetrasodium ethylenediaminetetraacetate hydrate
EC 200-573-9
C10H12N2Na4O8
Acetic acid, (ethylenedinitrilo)tetra-, tetrasodium salt
CHEMBL2104344
DTXSID3026350
Ethylenediaminetetraacetic acid, tetrasodium salt solution
CTK2F2895
KS-000000HU
ANW-56413
EDTA, Tetrasodium Salt, Ultra Pure
Glycine, N,N’-1,2-ethanediylbis(N-carboxymethyl-, tetrasodium salt
MFCD00012460
N,N’-1,2-Ethanediylbis(N-(carboxymethyl)glycine), tetrasodium salt
Sodium 2,2′,2”,2”’-(ethane-1,2-diylbis(azanetriyl))tetraacetate
AKOS015960370
Tetrasodium EDTA Tetrahydrate, Powder
DB13404
MCULE-6803567190
AC-10617
AK112806
SC-50859
E0099
E0565
FT-0626315
ST51037250
sodium salt of ethylenediamine tetracetic acid
D03946
ethylenediamine tetraacetic acid tetrasodium salt
ethylenediaminetetraacetic acid tetra sodium salt
A834617
ethylene diamine tetra acetic acid tetra sodium salt
J-006165
J-521350
Q27284152
Ethylenediamine tetraacetic acid tetrasodiumsalt, 86-88%
EDTA, Tetrasodium Tetrahydrate Salt – CAS 13235-36-4
tetrasodium 2,2′,2”,2”’-(ethane-1,2-diyldinitrilo)tetraacetate
tetrasodium 2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate
tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate
2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetic acid, sodium salt, sodium salt, sodium salt, sodium salt
tetrasodium 2-[2-[bis(2-oxidanidyl-2-oxidanylidene-ethyl)amino]ethyl-(2-oxidanidyl-2-oxidanylidene-ethyl)amino]ethanoat
Please call, or email, us if you need assistance in identifying the ions that need chelating, or in calculating the quantity of Tetrasodium EDTA.
info@atamankimya.com
Tel: 0090 216 577 10 10
SPECIFICATIONS
Appearance White Crystalline Powder
Odor Characteristic
Solubility Water Soluble
Storage Tightly Sealed / Protected from Heat and Moisture
Shelf 36 Months Properly Stored and Handled
ATTRIBUTES
Effective for a Variety of Metal Ions
Improves Hard Water Performance
Improves Preservative Efficacy
Improves Rinseability
Effective Neutralizer
Broad pH Range
APPLICATIONS
All Personal Care Products
Skin Care
Bath and Body Care
Hair Care
Tetrasodium EDTA is used to manufacture Styrene/Acrylates/Ammonium Methacrylate Copolymer. A chelating and stabilising agent, it helps chemical reactions to succeed.
Description
Tetrasodium EDTA is a salt of Ethylenediamine Tetraacetic Acid (EDTA), another chelating compound.
When creating a synthetic compound, several materials react together to obtain a new one. Often, they can contain minerals and metal ions that can prevent the reaction from taking place properly. This is where a chelating agent can come in handy. By sequestering these particles (grabbing onto them), it allows everything to go well and helps stabilise the final formula. The analogy we like the most is to describe this material as a lobster, with claws closing around the minerals as they float past in the water.
Since EDTA and its salts are used in a wide range of cosmetics, food, pharmaceuticals and household cleaning products, they have been the subject of in-depth studies since the 1980s as to their impact on the health and the environment. A regularly raised concern is that they are hardly biodegradable and are therefore found in most water systems. However, according to numerous studies, they aren’t of any problem for the environment or human and animal health as they don’t bioaccumulate and are quickly eliminated by organisms.
Applications
Cleaning products
Personal care and cosmetics
Indirect food contact
Cement additive
EDTA is an inhibitor of metalloproteases, at effective concentrations of 1-10 mM.
EDTA acts as a chelator of the zinc ion in the active site of metalloproteases, and can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases.
For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used.
The optimal concentration is 1.5 mg per ml of blood.
Preparation Note
Soluble in water at room temperature up to 1.45 M. The pH of this solution will be approximately 10 to 11 and will be rather viscous.
Synonyms:
edetate tetrasodium
ethylenediaminetetraacetic acid tetrasodium salt
( ethylenedinitrilo)tetraacetic acid tetrasodium salt
glycine, N,N’-1,2-ethanediylbis(N-(carboxymethyl)-, tetrasodium salt
sodium edetate
tetrasodium 2-[2-[bis(2-oxido-2-oxoethyl)amino]ethyl-(2-oxido-2-oxoethyl)amino] acetate
tetrasodium 2,2′,2”,2”’-(1,2-ethanediyldinitrilo)tetraacetate
tetrasodium 2,2′,2”,2”’-(ethane-1,2-diyldinitrilo)tetraacetate
tetrasodium edetate
tetrasodium EDTA
tetrasodium ethylene diamine tetraacetate
tetrasodium ethylenediamine-N,N,N’,N’-tetraacetate
tetrasodium ethylenediaminetetraacetate
Building and construction
Detailed description
Ethylenediaminetetraacetic acid, tetra sodium salt, 39% solution in water
Functions
Chelating agent
Applications
Detergents, Electroplating, Industrial Cleaning, Offshore Cleaning, Photography, Polymerization, Printing Ink, Catalytic Processes, Cement, Cleaning Food Industry, Agricultural Formulation, Textile Processing, Hard Surface Cleaning, Metal cleaning
Tetrasodium EDTA in soap
Why is it used?
EDTA (ethylene-diamine-tetra-acetic acid) is a chelator. It offers two benefits when used in soap. It increases the shelf life of your soap by chelating (binding up) certain metals that can cause DOS (dreaded orange spots, also known as rancidity). EDTA also reduces the amount of sticky soap scum formed when lye soap is used in hard water.
EDTA, sodium gluconate, and citrate do similar jobs, so if one does not appeal, then consider using the other. EDTA is arguably not as “crunchy” as citrate or sodium gluconate, so it is not the best choice for a “natural” soap. EDTA and sodium gluconate appear to be more effective than citrate in reducing soap scum.
What kind of EDTA to use?
There are two kinds of EDTA generally available to home crafters. TETRAsodium EDTA should be used in soap and other alkaline products. This is the type of EDTA that I am talking about in this article.
DIsodium EDTA is the other kind of EDTA; it should only be used in neutral pH to slightly acidic products. Disodium EDTA can be converted to the tetrasodium form if needed. But to keep soaping as simple as possible, I recommend buying the tetrasodium form.
Tetrasodium EDTA is available commercially in two forms — powder that is about 85% pure EDTA and a liquid solution of 39% EDTA in water. Either form can be used.
How to make your own EDTA solution?
EDTA powder is dusty and you only need tiny amounts, so I recommend making a 50% masterbatch EDTA solution and using this liquid when making soap rather than the powder.
Mix 1 part EDTA with 1 part distilled water by weight. Stir until the powder is dissolved. Store in a tightly closed container at room temperature.
How much EDTA to use in soap?
Typical dosage for bar (NaOH) soap or liquid (KOH) soap is 0.5% of EDTA powder based on total batch weight. This is 5 g EDTA powder per 1000 g of total batch weight. Total batch weight is the sum of the oil weight + water weight + alkali weight.
The range of dosages suggested by various sources is very wide — ranging from 0.05% to 4% of EDTA powder based on total batch weight. Here are some tips to help you decide —
To prevent rancidity (DOS) in soap, dosages range from 0.05% to 0.25% (0.5 g to 2.5 g EDTA powder per 1000 g total batch weight).
Kevin Dunn, author of the book Scientific Soapmaking, recommends 0.5 g EDTA per 1000 g oils to effectively control DOS. (Note his use of oil weight, not total batch weight.)
Dunn found a blend of 1.0 g rosemary oleoresin (ROE) plus 0.5 g EDTA powder added per 1000 g oils may be more effective at preventing DOS than either EDTA or ROE alone.
To also reduce hard water scum, a slightly higher dose of EDTA appears to be needed. Handcrafted soapers typically use 0.25% to 0.5% (2.5 g to 5 g powder per 1000 g batch weight) and get good results.
Use the lower percentage for soft water. Use the higher amount for hard water or if you are not sure about the hardness of the water.
How to measure EDTA?
The amount of EDTA powder needed is very small, so I think it is easier to use a homemade solution of EDTA and distilled water. Some suppliers sell a ready-to-use 39% EDTA solution.
You can make an EDTA solution in any concentration up to about 50% by weight (50 grams EDTA and 50 grams of distilled water). Measure the desired amount of EDTA powder and mix with distilled water until the EDTA is fully dissolved. Store in a labeled, airtight container.
If you know how much EDTA powder you want in a batch of soap, here is how to calculate the amount of 50% EDTA solution to use:
50% EDTA solution weight = 100 / 50 X (EDTA powder weight)
A simplified version of this formula for 50% EDTA solution:
50% EDTA solution weight = 2 X EDTA powder wt
If you are using an EDTA solution that is not 50%, then replace the “50” in first equation above with the correct percentage.
How much lye does it neutralize?
None! Do not adjust your lye weight for EDTA.
How should I add EDTA to my soap?
Blend EDTA solution into your fats along with any other additives you want to add to the fats, add the lye solution, and soap as usual. If using EDTA powder, mix the powder into water or water-based liquid (NOT the lye!) until the powder is dissolved and then blend this mixture into your fats.
CAUTION — Do NOT add tetrasodium EDTA to concentrated lye solution.
Tetrasodium EDTA will precipitate (turn into solid particles) in a concentrated alkali solution. This precipitation causes the lye solution to become a thick white “pudding.” EDTA needs to be dissolved to work properly, so do not use this “pudding” mixture to make soap.
If you make this mistake, one fix is to add sufficient water to the EDTA-lye mixture, and then stir for several minutes until the EDTA fully dissolves.
My experiments showed EDTA stays dissolved in NaOH below 35% concentration. Another soaper, however, said her EDTA precipitated in 33% NaOH solution. So you will have to experiment to find what works for you. If you let me know what you learn, I will update this article to be more accurate.
The other fix is to slowly flush the EDTA-lye mixture down the drain with lots of cold running water and start over.
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How to convert DIsodium EDTA to TETRAsodium EDTA?
Disclaimer — Other soap makers report this procedure works fine, but I do not personally have Disodium EDTA and have not personally tested the procedure. Try it at your own risk.
These instructions should make an approximately 50% mixture of TETRAsodium EDTA and water with a small excess of NaOH —
Distilled water 100 g
NaOH 22 g
Wearing gloves and eye protection, weigh the water and NaOH and mix them to make a lye solution. Let the lye cool until the solution is no more than pleasantly warm.
Disodium EDTA 100 g
Using good ventilation to control the dust, weigh the Disodium EDTA powder. Stir the powder into the lye solution until fully dissolved and the solution is clear.
Store this solution in a sturdy, leakproof container at room temperature. Since the mixture will be slightly alkaline (high pH), store this solution in a container that is safe for lye.
You would use this EDTA solution in your soap just as described above in the main article.
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Why is EDTA sold as a 39% solution?
You might be wondering why EDTA is sold as a 39% concentration. Why not just make a 50% mixture?
EDTA is used in industry to remove metal ions from water for steam boilers and other processes that use steam or hot water. It turns out 1 gram of 39% EDTA solution will chelate 1 millimole of metal ions.
When you are frequently adjusting the chelation dosage in an industrial process, using an easy-to-remember number like “1 gram EDTA per 1 millimole of metal ions” makes the calculations simpler and reduces the chance of error.
For soap makers, a 50% concentration makes more sense.