Streptozocin
| PubChem CID | 29327 |
|---|---|
| Structure |
Find Similar Structures
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| Chemical Safety |
Laboratory Chemical Safety Summary (LCSS) Datasheet
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| Molecular Formula | C8H15N3O7 |
| Synonyms |
streptozocin STREPTOZOTOCIN streptozosin Zanosar 18883-66-4 |
| Molecular Weight | 265.22 |
Streptozocin is a methylnitrosourea antineoplastic antibiotic isolated from the bacterium Streptomyces achromogenes. Streptozocin alkylates DNA, forming inter-strand DNA cross-links and inhibiting DNA synthesis. Due to its glucose moiety, this agent is readily taken up by pancreatic beta cells, inducing diabetes mellitus at high concentrations. Unlike other nitrosoureas, streptozocin causes little myelosuppression. (NCI04)