Quinine Sulfate
| PubChem CID | 16211610 |
|---|---|
| Structure |
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| Chemical Safety |
Laboratory Chemical Safety Summary (LCSS) Datasheet
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| Molecular Formula | C40H54N4O10S |
| Synonyms |
QUININE SULFATE DIHYDRATE quinine sulfate UNII-KF7Z0E0Q2B Qualaquin FEMA No. 2977 |
| Molecular Weight | 782.9 |
Quinine Sulfate is the sulfate salt form of the quinidine alkaloid isolate quinine. Quinine has many mechanisms of action, including reduction of oxygen intake and carbohydrate metabolism; disruption of DNA replication and transcription via DNA intercalation; and reduction of the excitability of muscle fibers via alteration of calcium distribution. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. (NCI04)