Quinidine
Summary
Quinidine is a medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
Brand Names: Nuedexta
Generic Name: Quinidine
DrugBank Accession Number: DB00908
Background
An optical isomer of quinine, extracted from the bark of the Cinchona tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular action potential, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.
Weight Average: 324.4168
Monoisotopic: 324.183778022
Chemical Formula: C20H24N2O2