Pyrazinamide
| PubChem CID | 1046 |
|---|---|
| Structure |
Find Similar Structures
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| Chemical Safety |
Laboratory Chemical Safety Summary (LCSS) Datasheet
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| Molecular Formula | C5H5N3O |
| Synonyms |
pyrazinamide pyrazinecarboxamide 98-96-4 pyrazine-2-carboxamide pyrazinoic acid amide |
| Molecular Weight | 123.11 |
Pyrazinamide is a synthetic pyrazinoic acid amide derivative with bactericidal property. Pyrazinamide is particularly active against slowly multiplying intracellular bacilli (unaffected by other drugs) by an unknown mechanism of action. Its bactericidal action is dependent upon the presence of bacterial pyrazinamidase, which removes the amide group to produce active pyrazinoic acid. Pyrazinamide is an important component of multidrug therapy for tuberculosis. (NCI04)