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Abstract Myeloproliferative neoplasm (MPN)-associated myelofibrosis (MF) is characterized by cytopenias, marrow fibrosis, constitutional symptoms, extramedullary hematopoiesis, splenomegaly, and shortened survival. Constitutive activation of the janus kinase/signal transducer and activator of transcription

Summary Febuxostat is a xanthine oxidase inhibitor used for the management of chronic hyperuricemia in adults with gout who have an inadequate response or intolerance to allopurinol. Background Febuxostat is a non-purine xanthine oxidase

Summary Everolimus is a mammalian target of rapamycin (mTOR) kinase inhibitor used to treat various types of malignancies. Background Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR

Summary Etoposide is a podophyllotoxin derivative used to treat testicular and small cell lung tumors. Background A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with

Summary Etodolac is an NSAID used to treat osteoarthritis and rheumatoid arthritis, as well as acute pain. Background Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects

Summary Ethiodized oil is a contrast agent used in imaging procedures Background Ethiodized oil is used by injection as a radio-opaque contrast agent. The composition of the oil is comprised of iodine combined with

PubChem CID 5991 Structure Find Similar Structures Chemical Safety Laboratory Chemical Safety Summary (LCSS) Datasheet Molecular Formula C20H24O2 Synonyms ethinyl estradiol Ethynylestradiol ETHINYLESTRADIOL 57-63-6 Ethynyl estradiol Molecular Weight 296.4  

Summary Eszopiclone is a sedative-hypnotic used in the treatment of insomnia, improving both the latency phase and the maintenance phase of sleep. Background Eszopiclone, marketed by Sepracor under the brand-name Lunesta, is a nonbenzodiazepine

PubChem CID 5284555 Structure Find Similar Structures Chemical Safety Laboratory Chemical Safety Summary (LCSS) Datasheet Molecular Formula C22H32N2O5S Synonyms Estropipate 7280-37-7 Piperazine estrone sulfate Piperazine estronesulfate Ogen Molecular Weight 436.6 Estropipate is a natural estrogenic substance composed of estrone sulfate and piperazine. Estropipate diffuses through the cell membrane and binds

PubChem CID 5757 Structure Find Similar Structures Chemical Safety Laboratory Chemical Safety Summary (LCSS) Datasheet Molecular Formula C18H24O2 Synonyms estradiol beta-Estradiol 17beta-Estradiol 50-28-2 Oestradiol Molecular Weight 272.4