2-Phenylethylamine
PubChem CID 1001 Structure Find Similar Structures Chemical Safety Laboratory Chemical Safety Summary (LCSS) Datasheet Molecular Formula C8H11N Synonyms Phenethylamine 2-phenylethylamine 2-Phenylethanamine 64-04-0 Benzeneethanamine Molecular Weight 121.18 2-phenylethylamine is a phenylethylamine having the phenyl substituent at the 2-position. It has a role as a human metabolite, an
Thalidomide
Abstract Thalidomide was a widely used drug in the late 1950s and early 1960s for the treatment of nausea in pregnant women. It became apparent in the 1960s that thalidomide treatment
Tadalafil and analogues
Abstract Modification of the hydantoin ring in the previously described lead compound 2a has led to the discovery of compound 12a, tadalafil, a highly potent and highly selective PDE5 inhibitor. The replacement of the
Sibutramine
Summary Sibutramine is a norepinephrine, serotonin and dopamine reuptake inhibitor indicated to assist with weight loss in obesity. Generic Name: Sibutramine Background Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries),
Sildenafil and analogues
Abstract The 5-[2-ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one, sildenafil, is a cGMP-specific phosphodiesterase-5 (PDE5) inhibitor used for penile erectile dysfunction. In the search for more potent and selective PDE5 inhibitors, new sildenafil analogues (6a−v), characterized by
Rosiglitazone
Summary Rosiglitazone is a thiazolidinedione indicated as an adjunct to diet and exercise to maintain glycemic control in type 2 diabetes. Brand Names: Avandamet, Avandia Generic Name: Rosiglitazone Weight Average: 357.427 Monoisotopic: 357.114712179 Chemical Formula: C18H19N3O3S
Rimonabant
PubChem CID 104850 Structure Find Similar Structures Chemical Safety Laboratory Chemical Safety Summary (LCSS) Datasheet Molecular Formula C22H21Cl3N4O Synonyms Rimonabant 168273-06-1 Acomplia 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide Zimulti Molecular Weight 463.8 Rimonabant is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. It is an inverse agonist for the cannabinoid receptor
Pioglitazone
Summary Pioglitazone is a thiazolidinedione used adjunctively with diet and exercise to normalize glycemic levels in adults with type 2 diabetes mellitus. Brand Names Actoplus Met, Actos, Duetact, Glidipion, Glubrava, Glustin, Incresync, Oseni, Tandemact Generic
Phenibut
Abstract Phenibut (beta-phenyl-gamma-aminobutyric acid HCl) is a neuropsychotropic drug that was discovered and introduced into clinical practice in Russia in the 1960s. It has anxiolytic and nootropic (cognition enhancing) effects. It
Nicotine
PubChem CID 89594 Structure Find Similar Structures Chemical Safety Laboratory Chemical Safety Summary (LCSS) Datasheet Molecular Formula C10H14N2 Synonyms nicotine L-Nicotine 54-11-5 (-)-Nicotine (S)-Nicotine Molecular Weight 162.23 Nicotine is a plant alkaloid, found in the tobacco plant, and addictive central nervous system (CNS) stimulant that causes either