Pioglitazone Hydrochloride
| PubChem CID | 60560 |
|---|---|
| Structure |
Find Similar Structures
|
| Chemical Safety |
Laboratory Chemical Safety Summary (LCSS) Datasheet
|
| Molecular Formula | C19H21ClN2O3S |
| Synonyms |
pioglitazone hydrochloride 112529-15-4 Pioglitazone HCl 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione hydrochloride Pioglitazone (hydrochloride) |
| Molecular Weight | 392.9 |
Pioglitazone Hydrochloride is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. Pioglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-gamma), a ligand-activated transcription factor, thereby inducing cell differentiation and inhibiting cell growth and angiogenesis. This agent also modulates the transcription of insulin-responsive genes, inhibits macrophage and monocyte activation, and stimulates adipocyte differentiation. (NCI05)