Oxaprozin
| PubChem CID | 4614 |
|---|---|
| Structure |
Find Similar Structures
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| Chemical Safety |
Laboratory Chemical Safety Summary (LCSS) Datasheet
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| Molecular Formula | C18H15NO3 |
| Synonyms |
oxaprozin 21256-18-8 Daypro 3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid Alvo |
| Molecular Weight | 293.3 |
Oxaprozin is a nonsteroidal anti-inflammatory drug (NSAID) derivative of oxazole-propionic acid with analgesic and antipyretic properties. As a first generation NSAID inhibitor, oxaprozin binds to and inactivates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of arachidonic acid to pro-inflammatory prostaglandins. When inhibiting COX-2, this agent may be effective in relieving pain and inflammation; when inhibiting COX-1, it may produce unacceptable gastrointestinal side effects. (NCI04)