Nebivolol
| PubChem CID | 71301 |
|---|---|
| Structure |
Find Similar Structures
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| Chemical Safety |
Laboratory Chemical Safety Summary (LCSS) Datasheet
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| Molecular Formula | C22H25F2NO4 |
| Synonyms |
Nebivolol 99200-09-6 2,2′-Azanediylbis(1-(6-fluorochroman-2-yl)ethanol) CHEBI:64019 Nebivololum [Latin] |
| Molecular Weight | 405.4 |
Nebivolol is a beta-1 adrenergic receptor antagonist with antihypertensive and vasodilatory activity. Nebivolol binds to and blocks the beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, nebivolol potentiates nitric oxide (NO), thereby relaxing vascular smooth muscle and exerting a vasodilatory effect.