Muromonab-cd3
Summary
Muromonab is a monoclonal anti-CD3 antibody used as immunosuppressive therapy in kidney, heart, and liver transplant patients.
Generic Name: Muromonab
DrugBank Accession Number: DB00075
Background
Murine monoclonal antibody specific to CD3 T-cell lymphocyte antigens. More specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured using the murine ascites method. Muromonab is 93% monomeric immune globulin G type 2a (IgG2a).
Protein Chemical Formula:C6460H9946N1720O2043S56
Protein Average Weight: 146189.7 Da