Isocarboxazid

Isocarboxazid

Summary

Isocarboxazid is a monoamine oxidase inhibitor used to treat enduring and debilitating symptoms of depression following inadequate clinical response to other antidepressant drugs.

Brand Names: Marplan

Generic Name: Isocarboxazid

Background

Isocarboxazid has the formula 1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine-isocarboxazid. It is a monoamine oxidase inhibitor.2 It is used in the treatment of major depression, dysthymic disorder, atypical disorder, panic disorder and the phobic disorders.4 It was first introduced by Roche pharmaceuticals, further developed by Validus pharms Inc and first FDA approved as a prescription drug on July 1st, 1959.

Weight Average: 231.2505
Monoisotopic: 231.100776675

Chemical Formula: C12H13N3O2

 

 

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