Idarubicin

Idarubicin

PubChem CID 42890
Structure
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Chemical Safety
Laboratory Chemical Safety Summary (LCSS) Datasheet
Molecular Formula C26H27NO9
Synonyms

IDARUBICIN

58957-92-9

4-Demethoxydaunorubicin

4-Demethoxydaunomycin

Idamycin

Molecular Weight 497.5

Idarubicin is a semisynthetic 4-demethoxy analogue of the antineoplastic anthracycline antibiotic daunorubicin. Idarubicin intercalates into DNA and interferes with the activity of topoisomerase II, thereby inhibiting DNA replication, RNA transcription and protein synthesis. Due to its high lipophilicity, idarubicin penetrates cell membranes more efficiently than other anthracycline antibiotic compounds.

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