Icodextrin
EXTRANEAL (Icodextrin 7.5%)
Solution for peritoneal dialysis
A sterile peritoneal dialysis fluid containing Icodextrin at a concentration of 7.5% w/v in an electrolyte solution.
| Icodextrin | 75 | g/L |
| Sodium Chloride | 5.4 | g/L |
| Sodium S-Lactate | 4.5 | g/L |
| Calcium Chloride | 0.257 | g/L |
| Magnesium Chloride | 0.051 | g/L |
Theoretical osmolarity: 284 (milliosmoles per litre)
Theoretical osmolality: 301 (milliosmoles per kg)
Electrolyte solution content per 1000 ml:
| Sodium | 133 | mmol/L |
| Calcium | 1.75 | mmol/L |
| Magnesium | 0.25 | mmol/L |
| Chloride | 96 | mmol/L |
| Lactate | 40 | mmol/L |
pH = 5 to 6
For the full list of excipients, see section 6.1.
Solution for peritoneal dialysis.
Extraneal is a sterile, clear, colorless solution.
Extraneal is recommended as a once daily replacement for a single glucose exchange as part of a continuous ambulatory peritoneal dialysis (CAPD) or automated peritoneal dialysis (APD) regimen for the treatment of chronic renal failure, particularly for patients who have lost ultrafiltration on glucose solutions, because it can extend time on CAPD therapy in such patients.