Gonadorelin

Gonadorelin

PubChem CID 638793
Structure
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Chemical Safety
Laboratory Chemical Safety Summary (LCSS) Datasheet
Molecular Formula C55H75N17O13
Synonyms

GONADORELIN

Luliberin

33515-09-2

LH-Releasing hormone

LH-Releasing factor

Molecular Weight 1182.3

Recombinant Gonadorelin is a synthetic luteinizing hormone releasing hormone (LHRH) identical to or similar to the endogenous hormone. Synthesized in and secreted by the hypothalamus, gonadorelin binds to transmembrane LHRH receptors on pituitary gonadotrophic cells, thereby stimulating synthesis and secretion of gonadotropins. Continuous administration of gonadorelin desensitizes the gonadotrophic cells, a negative feedback effect. This agent can be used in treatment of hypothalamic amenorrhea and evaluation of hypothalamic/pituitary function.

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