Everolimus

Everolimus

Summary

Everolimus is a mammalian target of rapamycin (mTOR) kinase inhibitor used to treat various types of malignancies.

Background

Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors Everolimus’ effect is solely on the mTORC1 protein and not on the mTORC2 protein.

WeightAverage: 958.24
Monoisotopic: 957.581356357

Chemical Formula: C₅₃H₈₃NO₁₄