Epirubicin Hydrochloride
| PubChem CID | 65348 |
|---|---|
| Structure |
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| Chemical Safety |
Laboratory Chemical Safety Summary (LCSS) Datasheet
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| Molecular Formula | C27H29NO11.ClH or C27H30ClNO11 |
| Synonyms |
Epirubicin hydrochloride Pharmorubicin Ellence 56390-09-1 Epirubicin HCl |
| Molecular Weight | 580.0 |
Epirubicin Hydrochloride is the hydrochloride salt of the 4′-epi-isomer of the anthracycline antineoplastic antibiotic doxorubicin. Epirubicin intercalates into DNA and inhibits topoisomerase II, thereby inhibiting DNA replication and ultimately, interfering with RNA and protein synthesis. This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation.