DISODIUM EDTA
DISODIUM EDTA
DISODIUM EDTA
Disodium EDTA is a chelant which binds to and deactivates several types of metal ions.
The effect helps to boost the preservative system of our products.
In Colorants this helps to preserve the intended color result and product stability in case of metal ion exposure during manufacturing of the tint.
Ethylenediaminetetraacetic acid disodium salt (EDTA 2Na) is used in detergents, liquid soap, shampoo, agricultural chemicals, fixer solution for development of color film, water cleaner, pH modifier. When stating the redox reaction for the polymerization of butyl benzene rubber, it is used as part of activator for the control of polymerization speed.
DISODIUM EDTA is an organic sodium salt that is the anhydrous form of the disodium salt of ethylenediaminetetraacetic acid (EDTA).
DISODIUM EDTA is formerly registered in the US for use as a disinfectant and component of contact lens solutions;
DISODIUM EDTA is used as a preservative, color retention agent, antioxidant, flavoring agent for foods, anticoagulant for blood collection, and chelating agent in personal care products;
DISODIUM EDTA is also used in the pulp and paper industry, in laboratory titrimetric analysis of metals, and as a therapeutic chelating agent;
DISODIUM EDTA is used in the agricultural, chemical, paper-pulp-board, textile processing, detergent, and cosmetics industries;
DISODIUM EDTA is used as a cleaning/washing agent, disinfectant, coloring agent, complexing agent, stabilizer, and micro-nutrient;
EC / List no.: 613-386-6
CAS no.: 6381-92-6
Ethylenediaminetetraacetic acid disodium salt (EDTA 2Na)
EDTA Na2 (ethylenediaminetetracetic acid disodium) is a chelating agent, used to sequester and decrease the reactivity of metal ions that may be present in many industrial and personal care products.
Industrial applications:
EDTA Na2 is used in cleaners, detergent, fertilizers, fixer solution for development of colour film, water cleaner and pH modifier. It is also used in redox reaction for the polymerization of butyl benzene rubber, it is used as part of activator for the control of polymerization speed.
Personal Care:
EDTA Na2 is used in Cosmetics to increase effectiveness and improve stability of bar and solid soaps, bath preparations; creams, oils, hair care products and many other personal care formulations.
SYNONYMS Disodium EDTA, disodium edetate; INS No. 386
DEFINITION
Chemical names Disodium salt of N,N’-1,2-Ethanediylbis[N-(carboxymethyl)glycine];
disodium dihydrogen ethylenediaminetetraacetate; disodium dihydrogen
(ethylene-dinitrilo)-tetraacetate
C.A.S. number 139-33-3
Chemical formula C10H14N2Na2O8 · 2H2O
Assay Not less than 99%
DESCRIPTION White, odourless crystalline granules or a white to nearly white powder
FUNCTIONAL USES Sequestrant, antioxidant synergist, preservative
EDTA is the commonly used abbreviation for (Ethylenedinitrilo)tetraacetic Acid (also called Ethylenediaminetetraacetic Acid or Edetic Acid). The Disodium salt of EDTA is the most commonly used form of this versatile organic complexing agent, which is used for the determination of many metal ions either by direct titration or by back-titration. Adjustment of reaction conditions, either by controlling the pH or by use of masking agents, and selection of the appropriate indicator permits a wide variety of metal ions to be determined using EDTA.
Molarity is best used in expressing EDTA concentration, because the reaction involves the complexation of one metal ion by one EDTA molecule or ion, whether the free acid form of EDTA or one of its more soluble Sodium salts is used. The general reaction involving the Disodium salt is:
EDTA2- + Mn+ → [EDTA-M]+n-2
where M = Ca, Mg, Cd, Mn, Ni, Al, Zn, Bi, Co, Cu, or other metal ion
An indicator is added that forms a colored complex with some of the metal ion being determined. When the endpoint is reached, all of the free metal ion has been complexed by the EDTA. The last addition of EDTA then removes the metal ion from its complex with the indicator, producing a color change. The relative strength of the EDTA-metal ion complex compared to that of the indicator-metal ion complex determines whether a direct titration or a back-titration is applicable.
EDTA is most commonly used to determine hardness (i.e., Calcium and Magnesium ions) in water, where the pH must be approximately 10 and is usually controlled by adding a buffer such as Water Hardness Buffer. Water Hardness Indicator (Eriochrome Black T), Eriochrome Blue Black R, Calmagite, and Murexide are used for hardness or Calcium determinations using EDTA.
Product Summary
Synonyms: Disodium dihydrogen ethylenediaminetetraacetate, Ethylenediaminetetraacetic acid disodium salt
CAS number: 6381-92-6
Hill Formula: C₁₀H₁₄N₂Na₂O₈*2H₂O
Molar mass: 372.24 g/mol
EDTA disodium salt (anhydrous) (CHEBI:64734) has part EDTA(2−) (CHEBI:64755)
EDTA disodium salt (anhydrous) (CHEBI:64734) has role chelator (CHEBI:38161)
EDTA disodium salt (anhydrous) (CHEBI:64734) is a organic sodium salt (CHEBI:38700)
Incoming EDTA disodium salt dihydrate (CHEBI:64758) has part EDTA disodium salt (anhydrous) (CHEBI:64734)
IUPAC Name
disodium 2,2′,2”,2”’-(ethane-1,2-diyldiammonio)tetraacetate
Synonyms Sources
(ethylenedinitrilo)tetraacetic acid disodium salt
disodium edetate
disodium edetate (anh.)
disodium edetate (anhydrous) ChEBI
disodium EDTA
disodium EDTA (anh.)
disodium EDTA (anhydrous)
edetate disodium
edetate disodium (anh.) ChEBI
edetate disodium (anhydrous)
Edetate disodium anhydrous
EDTA disodium ChEBI
EDTA disodium (anh.)
EDTA disodium (anhydrous)
EDTA disodium salt (anh.)
ethylenebis(iminodiacetic acid) disoidum salt
ethylenediaminetetraacetic acid disodium salt
N,N’-1,2-ethanediylbis[N-(carboxymethyl)glycine], disodium salt ChEBI
Na2-EDTA ChEBI
Na2H2EDTA ChEBI
DISODIUM EDTA
CAS number: 139-33-3 — 6381-92-6 – Disodium EDTA
Origin(s): Synthetic
Other languages: Dinatriumedta, EDTA disodique, Edta disódico
INCI name: DISODIUM EDTA
EINECS/ELINCS number: 205-358-3
Classification: EDTA
EDTA (EDTA and its main salts used in Disodium EDTA cosmetics, Tetrasodium EDTA, Trisodium EDTA) is a chelating agent that has been used since the 1930s and for which industrialists have complete control of processing and use. Its main property is to complex heavy metals. That is to say, it will somehow neutralize them by forming with them a complex, then serve them as carriers and evacuate them. It is therefore quite logically used in medicine to fight against heavy metal poisoning (lead for example).
It is often used as a sequestrant (calcium, limestone …) in soaps or shower gels, this allows to manage the “hard” water.
Its functions (INCI)
Chelating : Reacts and forms complexes with metal ions that could affect the stability and / or appearance of cosmetic products
Viscosity controlling : Increases or decreases the viscosity of cosmetics
EDTA disodium salt
(Ethylenedinitrilo)tetraacetic acid disodium salt
139-33-3 [RN]
2,2′,2”,2”’-(1,2-Éthanediyldinitrilo)tetraacétate de hydrogène et de sodium (1:2:2) [French] [ACD/IUPAC Name]
2,2′-{1,2-Éthanediylbis[(carboxyméthyl)imino]}diacétate de disodium [French] [ACD/IUPAC Name]
2,2′-{éthane-1,2-diylbis[(carboxyméthyl)imino]}diacétate de disodium [French]
Acetate, 2,2′,2”,2”’-(1,2-ethanediyldinitrilo)tetrakis-, hydrogen sodium salt (1:2:2) [ACD/Index Name]
Acetic acid, (ethylenedinitrilo)tetra-, disodium salt
Chelaplex III [Trade name]
Dinatrium-2,2′-{1,2-ethandiylbis[(carboxymethyl)imino]}diacetat [German] [ACD/IUPAC Name]
Dinatrium-2,2′-{ethan-1,2-diylbis[(carboxymethyl)imino]}diacetat [German]
Disodium 2,2′-{1,2-ethanediylbis[(carboxymethyl)imino]}diacetate [ACD/IUPAC Name]
disodium 2,2′-{ethane-1,2-diylbis[(carboxymethyl)imino]}diacetate
DISODIUM EDTA
Edetate disodium [BAN] [USAN] [USP]
Edetate disodium anhydrous
Edetic acid disodium salt
EDTA disodium
EDTA-Na2
Endrate disodium
ethylenediaminetetraacetic acid disodium
Ethylenediaminetetraacetic acid, disodium salt
MFCD00070672 [MDL number]
Natriumhydrogen-2,2′,2”,2”’-(1,2-ethandiyldinitrilo)tetraacetat (2:2:1) [German] [ACD/IUPAC Name]
Sodium hydrogen 2,2′,2”,2”’-(1,2-ethanediyldinitrilo)tetraacetate (2:2:1) [ACD/IUPAC Name]
Sodium N,N’-ethane-1,2-diylbis(N-(carboxymethyl)glycinate)
Tetracemate disodium
Titriplex III [Trade name]
Triplex III [Trade name]
Versene Disodium Salt
(Ethylenedinitrilo)-tetraacetic acid disodium salt
205-358-3 [EINECS]
Cheladrate
Chelaton 3
Chelaton III
Chelest 200
Chelest B
Clewat N
Collyrium Fresh-Eye Drops
Dinatrium ethylendiamintetraacetat [Czech]
Disodium (ethylenedinitrilo)tetraacetate
Disodium (ethylenedinitrilo)tetraacetic acid
DISODIUM 2-({2-[(CARBOXYLATOMETHYL)(CARBOXYMETHYL)AMINO]ETHYL}(CARBOXYMETHYL)AMINO)ACETATE
DISODIUM 2-({2-[BIS(CARBOXYMETHYL)AMINO]ETHYL}(CARBOXYLATOMETHYL)AMINO)ACETATE
disodium 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetate
disodium 2,2′,2”,2”’-(ethane-1,2-diyldiammonio)tetraacetate
disodium 2-[2-[bis(carboxymethyl)amino]ethyl-(2-oxido-2-oxo-ethyl)amino]acetate
Disodium diacid ethylenediaminetetraacetate
Disodium dihydrogen (ethylenedinitrilo)tetraacetate
Disodium dihydrogen ethylenediaminetetraacetate
disodium dihydrogen ethylenediaminetetraacetic acid
Disodium dihydrogen(ethylenedinitrilo)tetraacetate
Disodium edathamil
DISODIUM EDETATE
Disodium Edetate, Disodium EDTA, Ethylenedinitriletetraacetic Acid Disodium salt, N,N’-1,2-Ethanediyl-bis[N-(Carboxymethyl)Glycine
Disodium ethylenediamine-N,N,N’,N’-tetraacetate
disodium ethylene-diamine-tetra-acetate
DISODIUM ETHYLENEDIAMINETETRAACETATE
Disodium N,N’-1,2-ethanediylbis(N-(carboxymethyl)glycine)
DISODIUM SEQUESTRENE
Disodium tetracemate
Disodium versenate
Disodium versene
Disotate
Diso-Tate
Dotite 2NA
E.D.T.A. disodique [French]
Edathamil disodium
Edetate Disodium (anhydrous)
Edetate Sodium [USAN]
EDTA Disodium Salt 0.1 mol/l (0.1M) volumetric solution
Endrate [Trade name]
Ethylene diamine tetraacetic acid, disodium salt
Ethylenebis(iminodiacetic acid) disodium salt
ethylenebis(iminodiacetic acid) disoidum salt
ethylenediaminetetraacetate disodium
Ethylenediaminetetraacetate, disodium salt
Ethylenediaminetetraacetic acid disodium salt
Ethylenedinitrilotetraacetic acid disodium salt
Glycine, N,N’-1,2-ethanediylbis(N-(carboxymethyl)-, disodium salt
IDRANAL® 100
Kiresuto B
Komplexon III
Mavacid ED 4
Metaquest B
MFCD00012470 [MDL number]
MFCD00150037 [MDL number]
N,N’-1,2-Ethanediylbis(N-(carboxymethyl)glycine) disodium salt
N,N’-1,2-Ethanediylbis[N-(carboxymethyl)glycine] Disodium Salt
N,N’-1,2-ethanediylbis[N-(carboxymethyl)glycine], disodium salt
Na2-EDTA
Na2H2EDTA
Selekton B 2
Selekton B2
Sequestrene sodium 2
Sodium 2,2′-((2-(bis(carboxymethyl)amino)ethyl)azanediyl)diacetate
Sodium edetate
Sodium versenate [Trade name]
Titriplex(R) III solution
Trilon B
Trilon BD
Veresene disodium salt
Versene NA
Versene Na2
Versonol 120
Zonon D
E Edetate Disodium (EDTA)
Edetate disodium (EDTA) is a chelating agent that is utilized for its metal-binding properties.
It is best known as a treatment for calcific band keratopathy and has been used to neutralize corneal injuries due to calcium hydroxide, also known more commonly as lime burns.
As a preservative, it has shown to inactivate trace amounts of heavy metals in very low concentrations.
Disodium EDTA is in many products as a preservative, to stabilise it, or to enhance the foaming action.
It’s also used as a chelating agent, which means it us used to precipitate out metals from the formulation
Disodium EDTA
Disodium EDTA and the related ingredients bind to metal ions which inactivates them. The binding of metal ions helps prevent the deterioration of cosmetics and personal care products.
Disodium EDTA also helps to maintain clarity, protect fragrance compounds, and prevent rancidity.
Cosmetics
In shampoos, cleaners, and other personal care products, Disodium EDTA is used as a sequestering agent to improve their stability in air.
A chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive.
EDTA (ethylenediamine tetraacetic acid) and its salts, Calcium Disodium EDTA, Diammonium EDTA, Dipotassium EDTA, Disodium EDTA, TEA-EDTA, Tetrasodium EDTA, Tripotassium EDTA and Trisodium EDTA, and the related ingredients HEDTA (hydroxyethyl ethylenediamine triacetic acid) and its trisodium salt, Trisodium HEDTA, are crystalline powders often sold as aqueous solutions.
In cosmetics and personal care products, these ingredients are widely used and can be found in moisturizers, skin care and cleansing products, personal cleanliness products, bath soaps, shampoos and conditioners, hair dyes, hair bleaches, and many other product types.
EDTA, also known as edetic acid, and its salts were developed to counteract the effects of hard water and heavy metal ions in the manufacture of textiles.
These metal chelators are widely used in cosmetics and personal care products, in food, and in medicines.
Disodium EDTA forms complexes with calcium, magnesium, and iron, which allows for better foaming and cleaning performance of cosmetics and personal care products.
By binding with metal ions, Disodium EDTA prevents the metals from being deposited onto the hair, scalp and skin.
Disodium EDTA is a chelating agent which removes excess build-up of minerals.
Disodium EDTA is sold as a water soluble white powder that is slightly acidic.
It also enhances foaming and appeals to consumers who like this added feature.
Ethylenediaminetetraacetic acid (EDTA) is an aminopolycarboxylic acid with the formula [CH2N(CH2CO2H)2]2.
This white, water-soluble solid is widely used to bind to iron and calcium ions. It binds these ions as a hexadentate (“six-toothed”) chelating agent.
EDTA is produced as several salts, notably disodium EDTA, sodium calcium edetate, and tetrasodium EDTA
Disodium EDTA is mainly used to sequester metal ions in aqueous solution.
In the textile industry, it prevents metal ion impurities from modifying colours of dyed products.
In the pulp and paper industry, Disodium EDTA inhibits the ability of metal ions, especially Mn2+, from catalysing the disproportionation of hydrogen peroxide, which is used in chlorine-free bleaching.
In a similar manner, Disodium EDTA is added to some food as a preservative or stabiliser to prevent catalytic oxidative decolouration, which is catalysed by metal ions.
In soft drinks containing ascorbic acid and sodium benzoate, EDTA mitigates formation of benzene.[6]
The reduction of water hardness in laundry applications and the dissolution of scale in boilers both rely on EDTA and related complexants to bind Ca2+, Mg2+, as well as other metal ions.
Once bound to EDTA, these metal centres tend not to form precipitates or to interfere with the action of the soaps and detergents. For similar reasons, cleaning solutions often contain EDTA.
In a similar manner Disodium EDTA is used in the cement industry for the determination of free lime and free magnesia in cement and clinkers.
The solubilisation of Fe3+ ions at or below near neutral pH can be accomplished using EDTA.
This property is useful in agriculture including hydroponics.
However, given the pH dependence of ligand formation, EDTA is not helpful for improving iron solubility in above neutral soils.
Otherwise, at near-neutral pH and above, iron(III) forms insoluble salts, which are less bioavailable to susceptible plant species.
Aqueous [Fe(EDTA)]− is used for removing (“scrubbing”) hydrogen sulfide from gas streams.
This conversion is achieved by oxidising the hydrogen sulfide to elemental sulfur, which is non-volatile:
2 [Fe(EDTA)]− + H2S → 2 [Fe(EDTA)]2− + S + 2 H+
In this application, the iron(III) centre is reduced to its iron(II) derivative, which can then be reoxidised by air.
In similar manner, nitrogen oxides are removed from gas streams using [Fe(edta)]2−. The oxidising properties of [Fe(edta)]− are also exploited in photography, where it is used to solubilise silver particles.[4]
EDTA was used in separation of the lanthanide metals by ion-exchange chromatography.
Perfected by F. H. Spedding et al. in 1954, the method relies on the steady increase in stability constant of the lanthanide EDTA complexes with atomic number.
Using sulfonated polystyrene beads and Cu2+ as a retaining ion, EDTA causes the lanthanides to migrate down the column of resin while separating into bands of pure lanthanides.
The lanthanides elute in order of decreasing atomic number. Due to the expense of this method, relative to countercurrent solvent extraction, ion exchange is now used only to obtain the highest purities of lanthanides (typically greater than 99.99%)
edetate disodium (Q4532977)
chemical compound
Na2H2EDTA
disodium EDTA (anhydrous)
disodium EDTA
disodium EDTA (anh.)
edetate disodium (anhydrous)
disodium edetate (anhydrous)
EDTA disodium (anhydrous)
edetate disodium (anh.)
disodium edetate (anh.)
EDTA disodium salt (anh.)
EDTA disodium (anh.)
Edetate disodium anhydrous
Na2-EDTA
ethylenebis(iminodiacetic acid) disoidum salt
N,N’-1,2-ethanediylbis[N-(carboxymethyl)glycine], disodium salt
EDTA disodium
edetate disodium
disodium edetate
ethylenediaminetetraacetic acid disodium salt
(ethylenedinitrilo)tetraacetic acid disodium salt
edetate disodium anhydrous
Disodium ethylene diamine tetraacetate
Disodium ethylenediamine tetraacetate
Acid, Edetic
Acid, Ethylenediaminetetraacetic
Acid, Ethylenedinitrilotetraacetic
Calcitetracemate, Disodium
Calcium Disodium Edetate
Calcium Disodium Versenate
Calcium Tetacine
Chelaton 3
Chromium EDTA
Copper EDTA
Coprin
Dicobalt EDTA
Dinitrilotetraacetate, Disodium Ethylene
Dinitrilotetraacetate, Ethylene
Disodium Calcitetracemate
Disodium EDTA
Disodium Ethylene Dinitrilotetraacetate
Disodium Versenate, Calcium
Distannous EDTA
Edathamil
Edetate Disodium Calcium
Edetate, Calcium Disodium
Edetates
Edetic Acid
Edetic Acid, Calcium Salt
Edetic Acid, Calcium, Sodium Salt
Edetic Acid, Chromium Salt
Edetic Acid, Dipotassium Salt
Edetic Acid, Disodium Salt
Edetic Acid, Disodium Salt, Dihydrate
Edetic Acid, Disodium, Magnesium Salt
Edetic Acid, Disodium, Monopotassium Salt
Edetic Acid, Magnesium Salt
Edetic Acid, Monopotassium Salt
Edetic Acid, Monosodium Salt
Edetic Acid, Potassium Salt
Edetic Acid, Sodium Salt
EDTA
EDTA, Chromium
EDTA, Copper
EDTA, Dicobalt
EDTA, Disodium
EDTA, Distannous
EDTA, Gallium
EDTA, Magnesium Disodium
EDTA, Potassium
EDTA, Stannous
Ethylene Dinitrilotetraacetate
Ethylene Dinitrilotetraacetate, Disodium
Ethylenediaminetetraacetic Acid
Ethylenedinitrilotetraacetic Acid
Gallium EDTA
Magnesium Disodium EDTA
N,N’-1,2-Ethanediylbis(N-(carboxymethyl)glycine)
Potassium EDTA
Stannous EDTA
Tetacine, Calcium
Tetracemate
Versenate
Versenate, Calcium Disodium
Versene
Disodium EDTA
Edta disodium
139-33-3
Disodium ethylenediaminetetraacetic acid
SCHEMBL33500
disodium ethylenediamine tetracetic acid
ethylenediaminetetraacetic acid disodium
disodium ethylene diaminetetraacetic acid
disodium ethylenediamine tetraacetic acid
139D333
Ethylenediaminetetraacetic acid disodium salt solution, 0.01 M
Disodium N,N’-1,2-ethanediylbis(N-(carboxymethyl)glycine); (Ethylenedinitrilo)-tetraacetic acid disodium salt; Cheladrate; Chelaplex III; Chelaton 3; Chelaton III; Chelest 200; Chelest B; Clewat N; Complexon III; DR-16133; Dinatrium ethylendiamintetraacetat [Czech]; Diso-Tate; Disodium (ethylenedinitrilo)tetraacetate; Disodium (ethylenedinitrilo)tetraacetic acid; Disodium diacid ethylenediaminetetraacetate; Disodium dihydrogen ethylenediaminetetraacetate; Disodium dihydrogen(ethylenedinitrilo)tetraacetate; Disodium edathamil; Disodium edetate; Disodium EDTA, anhydrous; Disodium ethylenediamine-N,N,N’,N’-tetraacetate; Disodium ethylenediaminetetraacetate; Disodium ethylenediaminetetraacetic acid; Disodium salt of EDTA; Disodium sequestrene; Disodium tetracemate; Disodium versenate; Disodium versene; Dotite 2NA; E.D.T.A. disodique [French]; EDTA disodium; EDTA disodium salt; Edathamil disodium; Edetate disodium; Edetate sodium; Edetic acid disodium salt; Endrate disodium; Ethylenebis(iminodiacetic acid) disodium salt; Ethylenediaminetetraacetate, disodium salt; Ethylenediaminetetraacetic acid disodium salt; Ethylenediaminetetraacetic acid, disodium salt; F 1; F 1 (VAN); F 1 (complexon); Kiresuto B; Komplexon III; Mavacid ED 4; Metaquest B; N,N’-1,2-Ethanediylbis(N-(carboxymethyl)glycine) disodium salt; Perma Kleer 50 Crystals disodium salt; Perma Kleer Di Crystals; Selekton B 2; Sequestrene sodium 2; Sodium ethylenediaminetetraacetate; Sodium versenate; Tetracemate disodium; Titriplex III; Trilon BD; Triplex III; Veresene disodium salt; Versene NA; Versene Na2; Versonol 120; Zonon D; Ethylene diamine tetraacetic acid, disodium salt; Glycine, N,N’-1,2-ethanediylbis(N-(carboxymethyl)-, disodium salt; Glycine, N,N’-1,2-ethanediylbis(N-(carboxymethyl)-, sodium salt (1:2); Acetic acid, (ethylenedinitrilo)tetra-, disodium salt; [ChemIDplus]
2-[[]2-[[]bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid
Acetic acid, (ethylenedinitrilo)tetra-, disodium salt, dihydrate
Disodium dihydrogen ethylenediaminetetraacetate dihydrate
Disodium edetate
Disodium edetate dihydrate
Disodium EDTA dihydrate
Edetate disodium
EDTA disodium dihydrate
Endrate
Ethylenediaminetetraacetic acid disodium salt dihydrate
Ethylenediaminetetraacetic acid disoium salt dihydrate
Glycine, N,N’-1,2-ethanediylbis(N-(carboxymethyl)-, disodium salt, dihydrate
Glycine, N,N’-1,2-ethanediylbis[N-(carboxymethyl)-, sodium salt, hydrate (1:2:2)
Sodium versenate
IUPAC names
2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid
2-[[]2-[[]bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid
Dinatriumhydogenethylendiaminacetat
disodium 1-({2-(bis(2-oxopropyl)amino)ethyl)(2-oxopropyl)amonino)propan-2-one dihydrate
Disodium 2,2′,2”,2”’-(Ethane-1,2-diyldinitrilo)tetraacetate dihydrate
disodium 2-[carboxymethyl-[2-[carboxymethyl-(2-oxido-2-oxoethyl)amino]ethyl]amino]acetate
disodium 2-[carboxymethyl-[2-[carboxymethyl-(2-oxido-2-oxoethyl)amino]ethyl]amino]acetate dihydrate
Disodium edetate dihydrate
Disodium EDTA dihydrate
Edetate Disodium
Edetate Disodium
Edetate Disodium, dihydrate
EDTA Mn 13%
Ethylenediaminetetraacetic acid disodium salt dihydrate
Ethylenediaminetetraacetic acid, disodium, dihydrate
Glycine, N,N’-1,2-ethanediylbis[N-(carboxymethyl)-, disodium salt, dihydrate
Glycine, N,N’-1,2-ethanediylbis[N-(carboxymethyl)-, sodium salt, hydrate (1:2:2)
N,N’-1,2-ethanediylbis[N-(carboxymethyl)-, sodium salt, hydrate (1:2:2)
Trade names
Ethylenediaminetetraacetic Acid, Disodium Salt Dihydrate
Other names
Disodium edetate dihydrate
Ethylenediamine tetraacetic acid disodiumsalt dihydrate
Ethylenediaminetetraacetic acid disodium salt dihydrate
Glycine, N,N’-1,2-ethanediylbis[N-(carboxymethyl)-, disodium salt, dihydrate
Other identifiers
Code of Federal Regulations]
[Title 21, Volume 3]
[Revised as of April 1, 2020]
[CITE: 21CFR172.135]
TITLE 21–FOOD AND DRUGS
CHAPTER I–FOOD AND DRUG ADMINISTRATION
DEPARTMENT OF HEALTH AND HUMAN SERVICES
SUBCHAPTER B – FOOD FOR HUMAN CONSUMPTION (CONTINUED)
PART 172 — FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart B – Food Preservatives
Sec. 172.135 Disodium EDTA.
The food additive disodium edta (disodium ethylenediaminetetraacetate) may be safely used in designated foods for the purposes and in accordance with the following prescribed conditions:
(a) The additive contains a minimum of 99 percent disodium ethylenedia-minetetraacetate dihydrate (C10H14O8N2Na2-2H2O).
(b) It is used or intended for use as follows:
(1) Alone, in the following foods at not to exceed the levels prescribed, calculated as anhydrous calcium disodium edta :
Food Limitation (parts per million) Use
Aqueous multivitamin preparations 150 With iron salts as a stabilizer for vitamin B 12 in liquid multivitamin preparations.
Canned black-eyed peas 145 Promote color retention.
Canned kidney beans 165 Preservative.
Canned strawberry pie filling 500 Promote color retention.
Cooked sausage 36 As a cure accelerator with sodium ascorbate or ascorbic acid.
Dressings, nonstandardized 75 Preservative.
French dressing 75 Do.
Frozen white potatoes including cut potatoes 100 Promote color retention.
Gefilte fish balls or patties in packing medium 1 50 Inhibit discoloration.
Legumes (all cooked canned, other than black-eyed peas) 165 Promote color retention.
Mayonnaise 75 Preservative.
Ready-to-eat cereal products containing dried bananas 2 315 Promote color retention.
Salad dressing 75 Preservative.
Sandwich spread 100 Do.
Sauces 75 Do.
1 Based on total weight of finished product including packing medium.
2 In dried banana component of cereal product.
(2) With calcium disodium edta (calcium disodium ethylenediaminetetraacetate; calcium disodium (ethylenedinitrilo) tetraacetate), in the following foods at not to exceed, in combination, the levels prescribed, calculated as anhydrous C10H12O8N2CaNa2:
Food Limitation (parts per million) Use
Dressings, nonstandardized 75 Preservative.
French dressing 75 Do.
Mayonnaise 75 Do.
Salad dressing 75 Do.
Sandwich spread 100 Do.
Sauces 75 Do.
(3) Alone, as a sequestrant in the nonnutritive sweeteners that are listed in § 180.37 of this chapter and that, in addition, are designed for aqueous solution: Provided, That the amount of the additive, calculated as anhydrous calcium disodium edta , does not exceed 0.1 percent by weight of the dry nonnutritive sweetener.
(c) To assure the safe use of the additive:
(1) The label and labeling of the additive container shall bear, in addition to the other information required by the act, the name of the additive.
(2) The label or labeling of the additive container shall bear adequate use directions to provide a final food product that complies with the limitations provided in paragraph (b) of this section.
(d) In the standardized foods listed in paragraphs (b) (1) and (2) of this section the additives are used only in compliance with the applicable standards of identity for such foods.
[42 FR 14491, Mar. 15, 1977, as amended at 65 FR 48379, Aug. 8, 2000]
Preservative and sequestrant in foods Ethylenediaminetetraacetic acid, widely abbreviated as EDTA, is a polyamino carboxylic acid and a colourless, water-soluble solid.
Its conjugate base is named ethylenediaminetetraacetate. It is widely used to dissolve limescale.
Its usefulness arises because of its role as a hexadentate (“six-toothed”) ligand and chelating agent, i.e. its ability to “sequester” metal ions such as Ca2+ and Fe3+.
After being bound by EDTA, metal ions remain in solution but exhibit diminished reactivity.
EDTA is produced as several salts, notably disodium EDTA and calcium disodium EDTA. (Wikipedia)
Chelating agent used in food processing Ethylenediaminetetraacetic acid, widely abbreviated as EDTA, is a polyamino carboxylic acid and a colourless, water-soluble solid.
Its conjugate base is named ethylenediaminetetraacetate. It is widely used to dissolve limescale.
Its usefulness arises because of its role as a hexadentate (“six-toothed”) ligand and chelating agent, i.e. its ability to “sequester” metal ions such as Ca2+ and Fe3+.
After being bound by EDTA, metal ions remain in solution but exhibit diminished reactivity.
EDTA is produced as several salts, notably disodium EDTA and calcium disodium EDTA. (Wikipedia)
Sequestrant, preservative and discolouration inhibitor for foods Ethylenediaminetetraacetic acid, widely abbreviated as EDTA, is a polyamino carboxylic acid and a colourless, water-soluble solid.
Its conjugate base is named ethylenediaminetetraacetate.
It is widely used to dissolve limescale.
Its usefulness arises because of its role as a hexadentate (“six-toothed”) ligand and chelating agent, i.e. its ability to “sequester” metal ions such as Ca2+ and Fe3+.
After being bound by EDTA, metal ions remain in solution but exhibit diminished reactivity.
EDTA is produced as several salts, notably disodium EDTA and calcium disodium EDTA. (Wikipedia)
Ethylenediaminetetraacetic Acid, Disodium Salt, Dihydrate (Na2EDTA•2H2O), is a chelator of divalent metal cations.
DISODIUM EDTA
Disodium EDTA is a chelating agent. It is used in viscosity controlling.
Disodium EDTA deactivates the metal ions through bonding with them which inturn prevents cosmetic products from deteriorating.
A salt of an organic acid (Ethylenediaminetetraacetic Acid, disodium salt) used in aqueous solutions with other reagents and inert materials for the preparation of cleaning mixtures and poultices to be applied to stone surfaces and frescoes.
EDTA disodium salt, for its property of complexing calcium within crusts and for its good solubility (better than tetrasodium salt), is used in the AB 57 poultice (I.C.R. formulation – Rome).
It is besides a strong chelating agent of a great many metallic cations, as iron and copper; this property can be utilized to remove stains of rust or copper green from stone surfaces, wood, plasters, etc…