Dabigatran Etexilate

Dabigatran Etexilate

Summary

Dabigatran etexilate is an anticoagulant used for the prevention of venous thromboembolic events or stroke in patients with recent elective hip or knee replacement surgery and atrial fibrillation

Background
Dabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin inhibitor dabigatran.5,17,18 Dabigatran etexilate may be used to decrease the risk of venous thromboembolic events in patients in whom anticoagulation therapy is indicated.5 In contrast to warfarin, because its anticoagulant effects are predictable, lab monitoring is not necessary.5 Dabigatran etexilate was approved by the FDA in 2010.16

Chemical Formula: C34H41N7O5

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