Bexarotene
| PubChem CID | 82146 |
|---|---|
| Structure | |
| Chemical Safety |
Laboratory Chemical Safety Summary (LCSS) Datasheet
|
| Molecular Formula | C24H28O2 |
| Synonyms |
Bexarotene 153559-49-0 Targretin Targrexin LGD1069 |
| Molecular Weight | 348.5 |
Bexarotene is a synthetic retinoic acid agent with potential antineoplastic, chemopreventive, teratogenic and embryotoxic properties. Bexarotene selectively binds to and activates retinoid X receptors (RXRs), thereby inducing changes in gene expression that lead to cell differentiation, decreased cell proliferation, apoptosis of some cancer cell types, and tumor regression. (NCI04)