azidothymidine

azidothymidine

PubChem CID 35370
Structure
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Chemical Safety
Laboratory Chemical Safety Summary (LCSS) Datasheet
Molecular Formula C10H13N5O4
Synonyms

zidovudine

Azidothymidine

30516-87-1

3′-Azido-3′-deoxythymidine

Retrovir

Molecular Weight 267.24

Zidovudine is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. This agent also decreases levels of available pyrimidines. (NCI04)

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