Sirolimus
Summary
Sirolimus is an immunosuppressant used to prevent organ transplant rejections and to treat lymphangioleiomyomatosis.
Brand Names: Rapamune
Generic Name: Sirolimus
Background
A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to immunophilins. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.
Weight Average: 914.187
Monoisotopic: 913.555141608
Chemical Formula: C51H79NO13