Perindopril
| PubChem CID | 107807 |
|---|---|
| Structure |
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| Chemical Safety |
Laboratory Chemical Safety Summary (LCSS) Datasheet
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| Molecular Formula | C19H32N2O5 |
| Synonyms |
PERINDOPRIL 82834-16-0 Coversyl Perindoprilum S-9490 |
| Molecular Weight | 368.5 |
Perindopril is a non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Upon hydrolysis, perindopril is converted to its active form perindoprilat, inhibiting ACE and the conversion of angiotensin I to angiotensin II; consequently, angiotensin II-mediated vasoconstriction and angiotensin II-stimulated aldosterone secretion from the adrenal cortex are inhibited and diuresis and natriuresis ensue.