Olanzapine
Summary
Olanzapine is an antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders.
Brand Names: Olazax, Symbyax, Zalasta, Zypadhera, Zyprexa
Generic Name: Olanzapine
Background
Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent.2 The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions.5 Olanzapine very closely resembles clozapine and only differs by two additional methyl groups and the absence of a chloride moiety.10 It was discovered by scientists at Eli Lilly and approved to be marketed in the US in 1996.8
WeightAverage: 312.432
Monoisotopic: 312.14086735
Chemical Formula: C17H20N4S