Nelarabine
| PubChem CID | 3011155 |
|---|---|
| Structure |
Find Similar Structures
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| Chemical Safety |
Laboratory Chemical Safety Summary (LCSS) Datasheet
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| Molecular Formula | C11H15N5O5 |
| Synonyms |
Nelarabine Nelzarabine 121032-29-9 Arranon Atriance |
| Molecular Weight | 297.27 |
Nelarabine is an arabinonucleoside antimetabolite with antineoplastic activity. Nelarabine is demethoxylated by adenosine deaminase to become biologically active 9-beta-D-arabinosylguanine (ara-G); ara-G incorporates into DNA, thereby inhibiting DNA synthesis and inducing an S phase-dependent apoptosis of tumor cells. (NCI04)