Mitoxantrone Hydrochloride
| PubChem CID | 51082 |
|---|---|
| Structure |
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| Chemical Safety |
Laboratory Chemical Safety Summary (LCSS) Datasheet
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| Molecular Formula | C22H30Cl2N4O6 |
| Synonyms |
Mitoxantrone hydrochloride 70476-82-3 Mitoxantrone dihydrochloride Mitoxantrone HCl Novantrone |
| Molecular Weight | 517.4 |
Mitoxantrone Hydrochloride is the hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin.