Floxuridine
Summary
Floxuridine is an antimetabolite used as palliative management for liver metastases of gastrointestinal malignancy.
Background
An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection. Floxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution. When administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
WeightAverage: 246.1924
Monoisotopic: 246.065199677
Chemical Formula: C9H11FN2O5