NIPACIDE BIT 20
NIPACIDE BIT 20
Nipacide BIT 20 is an in-can biocide based on BIT.
Nipacide BIT 20 is a glycol based solution; low toxicity biocide developed for the complete in-can protection of water based products.
Nipacide BIT 20 is effective against a wide range of microorganisms including gram positive and gram negative bacteria, yeast and fungi.
Nipacide BIT 20 can be used over a wide pH and temperature range.
Nipacide BIT 20 should be the biocide of choice for products with pH >8 and production temperatures of >40 C.
Nipacide BIT 20 is a glycol based solution; low toxicity biocide developed for the complete in-can protection of water based products.
Nipacide BIT 20 is effective against a wide range of microorganisms including gram positive and gram negative bacteria, yeast and fungi.
Microorganisms grow at a rapid rate and without use of the correct
biocide, numbers can increase dramatically.
Benzisothiazolinone (BIT) is a organic compound with the formula C6H4SN(H)CO.
BIT is widely used as a preservative and antimicrobial.
Benzisothiazolinone has a microbicide and a fungicide mode of action. It is widely used as a preservative, for example in:
emulsion paints, caulks, varnishes, adhesives, inks, and photographic processing solutions
home cleaning and car care products; laundry detergents, stain removers and fabric softeners;
industrial settings, for example in textile spin-finish solutions, leather processing solutions, preservation of fresh animal hides and skins
agriculture in pesticide formulations
gas and oil drilling in muds and packer fluids preservation.
NIPACIDE BIT 20 is a broad spectrum biocide for the preservation of industrial water-based products against spoilage from bacteria, yeasts and fungi.
NIPACIDE BIT 20 is a 20% aqueous dipropylene glycol solution of 1,2-benzisothiazolin-3-one.
Applications
NIPACIDE BIT 20 is effective in a wide range of industrial aqueous-based products.
Application areas include:
• Synthetic polymer emulsions
• Emulsion paints
• Water-based adhesives
• Household products
• Printing inks
• Paper coating compositions
• Metal working fluids
• Agricultural pesticide dispersions
• Aqueous mineral and pigment slurries
• Tape joint compounds
• Leather processing solutions
Antimicrobial Properties
The levels of NIPACIDE BIT 20 needed to prevent the growth of problem micro-organisms are listed in Table 1.
MICs do not represent effective use levels but do indicate the broad spectrum of activity of NIPACIDE BIT 20.
NIPACIDE BIT 20 has a non-specific mode of action which means that bacterial resistance is very unlikely to occur.
Detailed information on the mode of action of NIPACIDE BIT 20 is available on request
Nipacide BIT 20 by Clariant is a formaldehyde-free, in-can biocide based on benzisothiazolinone (BIT).
It is an FDA approved, glycol-based solution exhibiting low toxicity.
Effective against a wide range of microorganisms including gram positive & gram negative bacteria, yeast and fungi.
It can be used over a wide pH and temperature range. Developed for the complete in-can protection of water-based decorative paints.
Recommended usage level of Nipacide® BIT 20 is 0.1 – 0.25%.
Table 2: Typical Physical Properties
Composition A solution of 1,2-benzisothiazolin3-one in dipropylene glycol and water.
Active agent 20% w/w
Physical form: Yellow-light brown solution
Viscosity at 10/25°C: 2000/400 mPa s (Newtonian)
pH at 25°C: 13.5
Boiling point: 100°C
Storage stability: Stable under normal conditions of storage down to -10°C.
If frozen,allow to thaw and stir well before use.
Active agent is heat-stable and non-volatile.
Flash point: Boils without flashing
Density at 25°C: 1.14
Compatibility: Compatible and effective over pH range 4-12.
Stable in the presence of amines.
Incompatible with some oxidising and reducing agents e.g. persalts, sulphites.
Amount to Use
NIPACIDE BIT 20 should be added to the system as early in the process as possible.
The concentration of NIPACIDE BIT 20 required to adequately preserve your product depends on several factors.
These include the susceptibility of the system to microbiological degradation, the extent to which micro-organisms can gain access, the species involved, pH, temperature, and length of time for which protection is required.
A range of concentrations and applications is recommended
in Table 3; however, it is recommended that a testing programme be undertaken to determine the most costeffective dose for your application.
Testing should take into account chemical compatibility/stability, plant hygiene conditions, susceptibility of the product to contamination, and the typical organisms involved.
Table 3: Applications
Product % NIPACIDE BIT 20 (w/w)
Synthetic polymer emulsions: 0.05-0.15
Emulsion paints: 0.05-0.15
Water-based adhesives: 0.05-0.25
Household products: 0.05-0.15
Including Laundry detergents, Fabric softeners,Dish-washing liquids, Floor and wall cleaning solutions, Surface cleaning products, Window cleaners,Floor polishes and waxes, Shoe polishes
Tape joint compounds: 0.05-0.25
Printing inks: 0.05-0.15
Paper coating compositions: 0.05-0.15
Metal working fluids: 0.05-0.18
Agricultural pesticide products: 0.05-0.25
Aqueous mineral and pigment slurries: 0.05-0.15
Leather processing solutions: 0.05-0.25
For the short term preservation of freshly flayed skins & hides during processing.
NIPACIDE BIT 20 by Lonza is a 20% aqueous dipropylene glycol solution of 1,2-benzisothiazolin-3-one.
Used for the preservation of industrial water-based products against spoilage from bacteria, yeasts and fungi.
It has a non-specific mode of action which means that bacterial resistance is very unlikely to occur.
It boils without flashing and is stable in the presence of amines. The concentration of NIPACIDE BIT 20 required to adequately preserve your product depends on several factors.
These include the susceptibility of the system to microbiological degradation, the extent to which micro-organisms can gain access, the species involved, pH, temperature, and length of time for which protection is required.
Suitable for use in synthetic polymer emulsions, emulsion paints, printing inks, paper coating compositions. Recommended dosage is 0.05-0.15% w/w for these applications.
NIPACIDE BIT 20 is an anti-bacterial, 19.3% active content, Formaldehyde free glycol/alcohol solution suitable for all types of formulations.
NIPACIDE BIT 20 Preservative, an aqueous solution of 1, 2- benzisothiazolin3-one, is an efficient microbiostat preservative for aqueous compositions such as oil in water emulsions.
Many aqueous dispersions and emulsions can be seriously impaired during storage and use due to the growth in them of bacteria and fungi.
NIPACIDE BIT 20 Preservative is an effective preservative against growth of the above microbial agents in the aqueous systems listed.
HOUSEHOLD CONSUMER, INDUSTRIAL, JANITORIAL PRODUCTS-LIQUID
For the control of bacteria and fungi in liquid soaps, liquid cleaners, liquid
detergents, liquid laundry products, liquid dishwashing detergents, waxes,
polishes, liquid fabric treatment/refresher products, liquid air
fresheners/deodorizers, car care products, and other similar cleaners.
Nipacide BIT 20 may also be used for the control of bacteria and fungi in package utility products including pre-moistened sponges and mops.
NIPACIDE BIT 20 may also be used for the control of bacteria and fungi in solutions that are then put into/onto wet wipes for use in industrial, commercial residential and household uses cited above.
Wet wipes containing a solution preserved with this product may not be used for personal care, as baby wipes, or for food contact.
NIPACIDE BIT 20 microbiocide may be added to those products formulated as concentrates which are in turn diluted for use at a level to ensure that the final usedilution product will contain between 0.05 – 0.20 % NIPACIDE BIT 20.