Avanafil
Summary
Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used to treat erectile dysfunction.
Brand Names: Spedra, Stendra
Generic Name: Avanafil
Background
Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both sildenafil and vardenafil but less selectivity than tadalafil, suggesting a relatively lower risk of visual disturbances associated with off-target PDE6 inhibition.5
It first received FDA approval on April 27, 2012,4 with subsequent EMA approval in June 2013.5